phosphoproteome analysis

Samples as above. Guideline protein input: 100-200 microgram (IMAC) or 500-1000 microgram (pTyr). Depending on workflow, prices range from ~230-250 euro / sample

Key publications:

Beekhof R, … Jimenez. Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer. Sci Transl Med. 2023 Aug 16;15(709):eabm3687.

Cordo’ V, …. Jimenez* & Meijerink*. Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies. Nat Commun. 2022 Feb 25;13(1):1048.

Beekhof R, … Jimenez. INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases. Mol Syst Biol. 2019 May 24;15(5):e8981.